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Pharmasin/Tylovet
Pharmasin/Tylovet
Contact Details
  • Company Name
  • Huvepharma
  • Contact Person
  • Tanya Koleva
  • Telephone
  • 359 - 28625331
  • Fax
  • 359 - 28625334
  • Town/City
  • Sofla
  • State/Province
  • Sofia
  • Country/Location
  • Bulgaria
  • Postal Code
  • 1113
  • Street Address
  • 5th Fllor
  • Website
  • http://www.huvepharma.com
Product Description
Product Name : Pharmasin/Tylovet
Unit Size : 20 kg
Packaging Type : 20 kg PE-lined multi-layer paper bags, oral granules 2%, Water soluble powder 100%, injectable 20% 100 ml
Product Origin : Bulgaria
PHARMASIN® 10% PREMIX
TYLOVET® 10% PREMIX

(tylosin phosphate)

COMPOSITION
Pharmasin/ Tylovet 10% premix
Tylosin phosphate equivalent to tylosin base 10 g
Excipients up to 100 g

PHARMACOLOGICAL ACTION
Tylosin is a macrolide antibiotic with a bacteriostatic effect (inhibiting the synthesis of the bacterial proteins) against Gram-positive and some Gram-negative microorganisms Streptococcus spp., Staphylococcus spp., Erysipelothrix spp., Corynebacterium spp., Brachyspira, Serpulina (Treponema) hyodysenteriae, Borrelia, Spirochaeta spp., Campylobacter (Vibrio) coli, Pasteurella spp., Brucella spp., Ricketsia spp., Mycoplasma spp., some large viruses, including also some anaerobic microorganisms (Fusobacterium spp., Bacteroides spp.), etc. It is active against Chlamidia spp. as well. Tylosin does not act antimicrobially directly on the bacteria of the family Enterobacteriaceae E. coli, Salmonella spp., but reveals an antiadhesive activity (hindering their adhesion on the intestinal vili, their penetration through the intestinal mucous membrane and impeding their colonization's phase as well). Tylosin proves also an anticoccidial activity mostly against Eimeria tenella. It also improves weight gain and feed conversion efficiency. Applied orally, the antibiotic is absorbed by the gastrointestinal tract not so intensively in comparison with the tartrate, but it penetrates in the target organs and tissues. Excretion is mainly through urine and bile, milk (in lactating animals) and eggs (in egg-producing poultry). It is compatible with tetracycline, sulphonamides, spectinomycin and the common dietary components of the feeds.

INDICATIONS
For prevention and treatment of infections caused by tylosin-sensitive pathogenic microorganisms - mycoplasmosis, chronic respiratory disease, an infectious synovitis in chickens and turkeys; infectious sinusitis in turkeys; spirochetosis (borreliosis) in chickens; dysentery in pigs; for prevention of liver abscesses (caused by Spherophorus necrophorus and Corynebacterium pyogenes) in calves for fattening.

CONTRAINDICATIONS
Tylosin must not be applied in lactating animals, the milk of which is intended for consumption or for technological processing. It must not be given to laying hens in poultry farms, which produce eggs for consumption (its use in stock layers is not contraindicated). It must not be included in compositions containing more than 2% of bentonite.

MODE OF ADMINISTRATION (Rp)
Orally, well homogenized into feed. In order to reach uniform homogenization with feed, it is recommended to mix the measured quantity of the preparation (calculated on the basis of the prescribed dose) on stages in the following order:
up to 10 kg feed; up to 100 kg feed; and up to 1000 kg feed.

TARGET SPECIES
Chickens, turkeys, pigs and calves for fattening.

DOSAGE
In grams per ton of feed:

WITHDRAWAL PERIOD
For meat:
Pigs - zero (0) days.
Poultry - 1 day after the last administration of the preparation.
Calves - zero (0) days.

SHELF LIFE
Two (2) years from the date of manufacture.
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